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Tau propagation is dependent on the genetic background of mouse strains

Progressive cognitive decline in Alzheimer’s disease correlates closely with the spread of tau protein aggregation across neural networks of the cortical mantle. We tested the hypothesis that heritable factors may influence the rate of propagation of tau pathology across brain regions in a model sys...

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Detalles Bibliográficos
Autores principales: Dujardin, Simon, Fernandes, Analiese, Bannon, Riley, Commins, Caitlin, De Los Santos, Mark, Kamath, Tarun V., Hayashi, Mansuo, Hyman, Bradley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952249/
https://www.ncbi.nlm.nih.gov/pubmed/35350555
http://dx.doi.org/10.1093/braincomms/fcac048