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Loss of Heterozygosity in the Tumor DNA of De Novo Diagnosed Patients Is Associated with Poor Outcome for B-ALL but Not for T-ALL

Despite the introduction of new technologies in molecular diagnostics, one should not underestimate the traditional routine methods for studying tumor DNA. Here we present the evidence that short tandem repeat (STR) profiling of tumor DNA relative to DNA from healthy cells might identify chromosomal...

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Detalles Bibliográficos
Autores principales: Risinskaya, Natalya, Kozhevnikova, Yana, Gavrilina, Olga, Chabaeva, Julia, Kotova, Ekaterina, Yushkova, Anna, Isinova, Galina, Zarubina, Ksenija, Obukhova, Tatiana, Kulikov, Sergey, Julhakyan, Hunan, Sudarikov, Andrey, Parovichnikova, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952291/
https://www.ncbi.nlm.nih.gov/pubmed/35327952
http://dx.doi.org/10.3390/genes13030398