A Histone Deacetylase (HDAC) Inhibitor with Pleiotropic In Vitro Anti-Toxoplasma and Anti-Plasmodium Activities Controls Acute and Chronic Toxoplasma Infection in Mice

Toxoplasmosis is a highly prevalent human disease, and virulent strains of this parasite emerge from wild biotopes. Here, we report on the potential of a histone deacetylase (HDAC) inhibitor we previously synthesized, named JF363, to act in vitro against a large panel of Toxoplasma strains, as well...

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Detalles Bibliográficos
Autores principales: Jublot, Delphine, Cavaillès, Pierre, Kamche, Salima, Francisco, Denise, Fontinha, Diana, Prudêncio, Miguel, Guichou, Jean-Francois, Labesse, Gilles, Sereno, Denis, Loeuillet, Corinne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952293/
https://www.ncbi.nlm.nih.gov/pubmed/35328672
http://dx.doi.org/10.3390/ijms23063254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952293/
https://www.ncbi.nlm.nih.gov/pubmed/35328672
http://dx.doi.org/10.3390/ijms23063254

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