One-Step Synthesis of Nanoliposomal Copper Diethyldithiocarbamate and Its Assessment for Cancer Therapy

The metal complex copper diethyldithiocarbamate (CuET) induces cancer cell death by inhibiting protein degradation and induces proteotoxic stress, making CuET a promising cancer therapeutic. However, no clinical formulation of CuET exists to date as the drug is insoluble in water and exhibits poor b...

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Detalles Bibliográficos
Autores principales: Paun, Radu A., Dumut, Daciana C., Centorame, Amanda, Thuraisingam, Thusanth, Hajduch, Marian, Mistrik, Martin, Dzubak, Petr, De Sanctis, Juan B., Radzioch, Danuta, Tabrizian, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952320/
https://www.ncbi.nlm.nih.gov/pubmed/35336014
http://dx.doi.org/10.3390/pharmaceutics14030640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952320/
https://www.ncbi.nlm.nih.gov/pubmed/35336014
http://dx.doi.org/10.3390/pharmaceutics14030640

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