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One-Step Synthesis of Nanoliposomal Copper Diethyldithiocarbamate and Its Assessment for Cancer Therapy
The metal complex copper diethyldithiocarbamate (CuET) induces cancer cell death by inhibiting protein degradation and induces proteotoxic stress, making CuET a promising cancer therapeutic. However, no clinical formulation of CuET exists to date as the drug is insoluble in water and exhibits poor b...
Autores principales: | Paun, Radu A., Dumut, Daciana C., Centorame, Amanda, Thuraisingam, Thusanth, Hajduch, Marian, Mistrik, Martin, Dzubak, Petr, De Sanctis, Juan B., Radzioch, Danuta, Tabrizian, Maryam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952320/ https://www.ncbi.nlm.nih.gov/pubmed/35336014 http://dx.doi.org/10.3390/pharmaceutics14030640 |
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