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Dedifferentiation of Human Cardiac Myofibroblasts Is Independent of Activation of COX-2/PGE(2) Pathway

The differentiation of cardiac fibroblasts to myofibroblasts is considered to be a critical step in activation and progression of cardiac fibrosis in heart disease. TGF-β is one of the key cytokines that promotes transition of fibroblasts to myofibroblasts. Dedifferentiation of formed myofibroblasts...

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Detalles Bibliográficos
Autores principales: Luu, Vy Tran, Phan, Sang, Jin, Zhu-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952377/
https://www.ncbi.nlm.nih.gov/pubmed/35328443
http://dx.doi.org/10.3390/ijms23063023