Role of C-Terminal Domain and Membrane Potential in the Mobility of Kv1.3 Channels in Immune Synapse Forming T Cells

Voltage-gated Kv1.3 potassium channels are essential for maintaining negative membrane potential during T-cell activation. They interact with membrane-associated guanylate kinases (MAGUK-s) via their C-terminus and with TCR/CD3, leading to enrichment at the immunological synapse (IS). Molecular inte...

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Detalles Bibliográficos
Autores principales: Sebestyén, Veronika, Nagy, Éva, Mocsár, Gábor, Volkó, Julianna, Szilágyi, Orsolya, Kenesei, Ádám, Panyi, György, Tóth, Katalin, Hajdu, Péter, Vámosi, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952507/
https://www.ncbi.nlm.nih.gov/pubmed/35328733
http://dx.doi.org/10.3390/ijms23063313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952507/
https://www.ncbi.nlm.nih.gov/pubmed/35328733
http://dx.doi.org/10.3390/ijms23063313

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