Cargando…

mTORC2 suppresses cell death induced by hypo-osmotic stress by promoting sphingomyelin transport

Epithelial cells are constantly exposed to osmotic stress. The influx of water molecules into the cell in a hypo-osmotic environment increases plasma membrane tension as it rapidly expands. Therefore, the plasma membrane must be supplied with membrane lipids since expansion beyond its elastic limit...

Descripción completa

Detalles Bibliográficos
Autores principales: Ono, Yumiko, Matsuzawa, Kenji, Ikenouchi, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952684/
https://www.ncbi.nlm.nih.gov/pubmed/35319770
http://dx.doi.org/10.1083/jcb.202106160