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mTORC2 suppresses cell death induced by hypo-osmotic stress by promoting sphingomyelin transport
Epithelial cells are constantly exposed to osmotic stress. The influx of water molecules into the cell in a hypo-osmotic environment increases plasma membrane tension as it rapidly expands. Therefore, the plasma membrane must be supplied with membrane lipids since expansion beyond its elastic limit...
Autores principales: | Ono, Yumiko, Matsuzawa, Kenji, Ikenouchi, Junichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952684/ https://www.ncbi.nlm.nih.gov/pubmed/35319770 http://dx.doi.org/10.1083/jcb.202106160 |
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