mRNA Lipoplexes with Cationic and Ionizable α-Amino-lipophosphonates: Membrane Fusion, Transfection, mRNA Translation and Conformation

Cationic liposomes are attractive carriers for mRNA delivery. Here, mRNA lipoplexes (LX) were prepared with the cationic lipids α-aminolipophosphonate (3b) or imidazolium lipophosphoramidate (2) associated with various α-aminolipophosphonates co-lipids comprising protonable groups (imidazole or pyri...

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Detalles Bibliográficos
Autores principales: Akhter, Sohail, Berchel, Mathieu, Jaffrès, Paul-Alain, Midoux, Patrick, Pichon, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952827/
https://www.ncbi.nlm.nih.gov/pubmed/35335957
http://dx.doi.org/10.3390/pharmaceutics14030581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952827/
https://www.ncbi.nlm.nih.gov/pubmed/35335957
http://dx.doi.org/10.3390/pharmaceutics14030581

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