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Combined impact of lipidomic and genetic aberrations on clinical outcomes in metastatic castration-resistant prostate cancer

BACKGROUND: Both changes in circulating lipids represented by a validated poor prognostic 3-lipid signature (3LS) and somatic tumour genetic aberrations are individually associated with worse clinical outcomes in men with metastatic castration-resistant prostate cancer (mCRPC). A key question is how...

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Detalles Bibliográficos
Autores principales: Mak, Blossom, Lin, Hui-Ming, Kwan, Edmond M., Fettke, Heidi, Tran, Ben, Davis, Ian D., Mahon, Kate, Stockler, Martin R., Briscoe, Karen, Marx, Gavin, Zhang, Alison, Crumbaker, Megan, Tan, Winston, Huynh, Kevin, Meikle, Thomas G., Mellett, Natalie A., Hoy, Andrew J., Du, Pan, Yu, Jianjun, Jia, Shidong, Joshua, Anthony M., Waugh, David J., Butler, Lisa M., Kohli, Manish, Meikle, Peter J., Azad, Arun A., Horvath, Lisa G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953070/
https://www.ncbi.nlm.nih.gov/pubmed/35331214
http://dx.doi.org/10.1186/s12916-022-02298-0