MiR-183-5p Induced by Saturated Fatty Acids Hinders Insulin Signaling by Downregulating IRS-1 in Hepatocytes

Excessive saturated fatty acids (SFA) uptake is known to be a primary cause of obesity, a widely acknowledged risk factor of insulin resistance and type 2 diabetes. Although specific microRNAs (miRNAs) targeting insulin signaling intermediates are dysregulated by SFA, their effects on insulin signal...

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Detalles Bibliográficos
Autores principales: Nguyen, Mai Thi, Min, Kyung-Ho, Lee, Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953084/
https://www.ncbi.nlm.nih.gov/pubmed/35328400
http://dx.doi.org/10.3390/ijms23062979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953084/
https://www.ncbi.nlm.nih.gov/pubmed/35328400
http://dx.doi.org/10.3390/ijms23062979

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