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The CD3ζ adaptor structure determines functional differences between human and mouse CD16 Fc receptor signaling

Natural killer (NK) cells can detect antibody-coated cells through recognition by the CD16 Fc receptor. The importance of CD16 in human NK cell biology has long been appreciated, but how CD16 functions in mouse NK cells remains poorly understood. Here, we report drastic differences between human and...

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Detalles Bibliográficos
Autores principales: Aguilar, Oscar A., Fong, Lam-Kiu, Ishiyama, Kenichi, DeGrado, William F., Lanier, Lewis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953085/
https://www.ncbi.nlm.nih.gov/pubmed/35320345
http://dx.doi.org/10.1084/jem.20220022