Cargando…

The CD3ζ adaptor structure determines functional differences between human and mouse CD16 Fc receptor signaling

Natural killer (NK) cells can detect antibody-coated cells through recognition by the CD16 Fc receptor. The importance of CD16 in human NK cell biology has long been appreciated, but how CD16 functions in mouse NK cells remains poorly understood. Here, we report drastic differences between human and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aguilar, Oscar A., Fong, Lam-Kiu, Ishiyama, Kenichi, DeGrado, William F., Lanier, Lewis L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953085/ https://www.ncbi.nlm.nih.gov/pubmed/35320345 http://dx.doi.org/10.1084/jem.20220022

Ejemplares similares

The Adaptor Protein SAP Directly Associates with CD3ζ Chain and Regulates T Cell Receptor Signaling
por: Proust, Richard, et al.
Publicado: (2012)

Src-like adaptor protein down-regulates T cell receptor (TCR)–CD3 expression by targeting TCRζ for degradation
por: Myers, Margaret D., et al.
Publicado: (2005)

Gene-modified NK-92MI cells expressing a chimeric CD16-BB-ζ or CD64-BB-ζ receptor exhibit enhanced cancer-killing ability in combination with therapeutic antibody
por: Chen, Ying, et al.
Publicado: (2017)

Function and evolution of the prototypic CD28ζ and 4-1BBζ chimeric antigen receptors
por: Feucht, J., et al.
Publicado: (2020)

Factor VIII-Fc Activates Natural Killer Cells via Fc-Mediated Interactions With CD16
por: Lagassé, H.A. Daniel, et al.
Publicado: (2021)

Activated Platelets Convert CD14(+)CD16(-) Into CD14(+)CD16(+) Monocytes With Enhanced FcγR-Mediated Phagocytosis and Skewed M2 Polarization
por: Lee, Su Jeong, et al.
Publicado: (2021)

Signal transduction by the CD2 antigen in T cells and natural killer cells: requirement for expression of a functional T cell receptor or binding of antibody Fc to the Fc receptor, Fc gamma RIIIA (CD16)
Publicado: (1991)

T Cell Development in Mice Lacking All T Cell Receptor ζ Family Members (ζ, η, and FcεRIγ)
por: Shores, Elizabeth W., et al.
Publicado: (1998)

ERK Activation in CAR T Cells Is Amplified by CD28-Mediated Increase in CD3ζ Phosphorylation
por: Rohrs, Jennifer A., et al.
Publicado: (2020)

MiR-214 regulates CD3ζ expression in T cells
por: Xiao, Yankai, et al.
Publicado: (2019)

Signal transduction by Fc gamma RIII (CD16) is mediated through the gamma chain
Publicado: (1992)

CD16. Developmentally regulated IgG Fc receptors on cultured human monocytes
Publicado: (1988)

High-affinity CD16-polymorphism and Fc-engineered antibodies enable activity of CD16-chimeric antigen receptor-modified T cells for cancer therapy
por: Rataj, Felicitas, et al.
Publicado: (2018)

Association of CD247 (CD3ζ) gene polymorphisms with T1D and AITD in the population of northern Sweden
por: Holmberg, Dan, et al.
Publicado: (2016)

The levels of CD16/Fc gamma receptor III A on CD14(+)CD16(+) monocytes are higher in children with severe Plasmodium falciparum anemia than in children with cerebral or uncomplicated malaria
por: Ogonda, Lilian A, et al.
Publicado: (2010)

Engineering Cytoplasmic Signaling of CD28ζ CARs for Improved Therapeutic Functions
por: Meng, Xianhui, et al.
Publicado: (2020)

The Low Expression of Fc-Gamma Receptor III (CD16) and High Expression of Fc-Gamma Receptor I (CD64) on Neutrophil Granulocytes Mark Severe COVID-19 Pneumonia
por: Hoffmann, Joerg, et al.
Publicado: (2022)

Cross-Talk between TLR4 and FcγReceptorIII (CD16) Pathways
por: Rittirsch, Daniel, et al.
Publicado: (2009)

T Lymphocytes from Chagasic Patients Are Activated but Lack Proliferative Capacity and Down-Regulate CD28 and CD3ζ
por: Giraldo, Nicolás A., et al.
Publicado: (2013)

The antibody-binding Fc gamma receptor IIIa / CD16a is N-glycosylated with high occupancy at all five sites
por: Lampros, Elizabeth A., et al.
Publicado: (2022)

Degradation of T Cell Receptor (TCR)–CD3-ζ Complexes after Antigenic Stimulation
por: Valitutti, Salvatore, et al.
Publicado: (1997)

Fcγ receptor binding is required for maximal immunostimulation by CD70-Fc
por: Dadas, Osman, et al.
Publicado: (2023)

Polymorphisms of CD16A and CD32 Fcγ receptors and circulating immune complexes in Ménière's disease: a case-control study
por: Lopez-Escamez, José A, et al.
Publicado: (2011)

Examination of IgG Fc Receptor CD16A and CD64 Expression by Canine Leukocytes and Their ADCC Activity in Engineered NK Cells
por: Hullsiek, Robert, et al.
Publicado: (2022)

CD28 expression in sentinel node biopsies from breast cancer patients in comparison with CD3-ζ chain expression
por: Schüle, Jana M, et al.
Publicado: (2004)

CD16 (FcRγIII) as a potential marker of osteoclast precursors in psoriatic arthritis
por: Chiu, Yahui Grace, et al.
Publicado: (2010)

Rapid Decrease of CD16 (FcγRIII) Expression on Heat-Shocked Neutrophils and Their Recognition by Macrophages
por: Bzowska, Małgorzata, et al.
Publicado: (2011)

Single-cell quantification of functional outcomes of CD16 ligation in NK cells by Fc-engineered antibodies
por: Romain, Gabrielle, et al.
Publicado: (2013)

Fc gamma R(CD16) interaction with ligand induces Ca2+ mobilization and phosphoinositide turnover in human natural killer cells. Role of Ca2+ in Fc gamma R(CD16)-induced transcription and expression of lymphokine genes
Publicado: (1989)

CD56(neg)CD16(+) NK cells are activated mature NK cells with impaired effector function during HIV-1 infection
por: Milush, Jeffrey M, et al.
Publicado: (2013)

Functional properties of a unique subset of cytotoxic CD3+ T lymphocytes that express Fc receptors for IgG (CD16/Leu-11 antigen)
Publicado: (1985)

T Cell Receptor Engagement Triggers Its CD3ε and CD3ζ Subunits to Adopt a Compact, Locked Conformation
por: Risueño, Ruth M., et al.
Publicado: (2008)

CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering
por: Oostindie, Simone C., et al.
Publicado: (2019)

159. efficacy of CD377, a Novel Antiviral Fc-conjugate, Against Seasonal Influenza in Lethal Mouse Infection Models
por: Levin, James, et al.
Publicado: (2020)

Physical and functional association of p56lck with Fc gamma RIIIA (CD16) in natural killer cells
Publicado: (1993)

CD24Fc: an emerging COVID-19 therapy
por: Eckhardt, Christina M, et al.
Publicado: (2022)

LIME: A New Membrane Raft-associated Adaptor Protein Involved in CD4 and CD8 Coreceptor Signaling
por: Brdičková, Naděžda, et al.
Publicado: (2003)

Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques
por: Tolbert, William D., et al.
Publicado: (2022)

Quantitative serum determination of CD3, CD4, CD8, CD16, and CD56 in women with primary infertility: The role of cell-mediated immunity
por: Shakerian, Behzad, et al.
Publicado: (2022)

Down Regulation of the TCR Complex CD3ζ-Chain on CD3+ T Cells: A Potential Mechanism for Helminth-Mediated Immune Modulation
por: Appleby, Laura J., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_d5qafd6pr4gonr0vlgbiflau2a