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Programmed Cell Death Alterations Mediated by Synthetic Indole Chalcone Resulted in Cell Cycle Arrest, DNA Damage, Apoptosis and Signaling Pathway Modulations in Breast Cancer Model

Although new chemotherapy significantly increased the survival of breast cancer (BC) patients, the use of these drugs is often associated with serious toxicity. The discovery of novel anticancer agents for BC therapy is expected. This study was conducted to explore the antiproliferative effect of ne...

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Detalles Bibliográficos
Autores principales: Michalkova, Radka, Kello, Martin, Kudlickova, Zuzana, Gazdova, Maria, Mirossay, Ladislav, Mojzisova, Gabriela, Mojzis, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953149/
https://www.ncbi.nlm.nih.gov/pubmed/35335879
http://dx.doi.org/10.3390/pharmaceutics14030503