The Transthyretin/Oleuropein Aglycone Complex: A New Tool against TTR Amyloidosis

The release of monomers from the homotetrameric protein transthyretin (TTR) is the first event of a cascade, eventually leading to sporadic or familial TTR amyloidoses. Thus, ligands able to stabilize TTR and inhibit monomer release are subject of intense scrutiny as potential treatments against the...

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Detalles Bibliográficos
Autores principales: Bemporad, Francesco, Leri, Manuela, Ramazzotti, Matteo, Stefani, Massimo, Bucciantini, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953266/
https://www.ncbi.nlm.nih.gov/pubmed/35337074
http://dx.doi.org/10.3390/ph15030277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953266/
https://www.ncbi.nlm.nih.gov/pubmed/35337074
http://dx.doi.org/10.3390/ph15030277

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