Cargando…
The Transthyretin/Oleuropein Aglycone Complex: A New Tool against TTR Amyloidosis
The release of monomers from the homotetrameric protein transthyretin (TTR) is the first event of a cascade, eventually leading to sporadic or familial TTR amyloidoses. Thus, ligands able to stabilize TTR and inhibit monomer release are subject of intense scrutiny as potential treatments against the...
Autores principales: | Bemporad, Francesco, Leri, Manuela, Ramazzotti, Matteo, Stefani, Massimo, Bucciantini, Monica |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953266/ https://www.ncbi.nlm.nih.gov/pubmed/35337074 http://dx.doi.org/10.3390/ph15030277 |
Ejemplares similares
-
Oleuropein aglycone stabilizes the monomeric α-synuclein and favours the growth of non-toxic aggregates
por: Palazzi, Luana, et al.
Publicado: (2018) -
The Protective Role of Oleuropein Aglycone against Pesticide-Induced Toxicity in a Human Keratinocytes Cell Model
por: Leri, Manuela, et al.
Publicado: (2023) -
Healthspan Maintenance and Prevention of Parkinson’s-like Phenotypes with Hydroxytyrosol and Oleuropein Aglycone in C. elegans
por: Brunetti, Giovanni, et al.
Publicado: (2020) -
Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2‐microglobulin
por: Leri, Manuela, et al.
Publicado: (2016) -
The Polyphenol Oleuropein Aglycone Protects TgCRND8 Mice against Aß Plaque Pathology
por: Grossi, Cristina, et al.
Publicado: (2013)