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Long-Acting Thioredoxin Ameliorates Doxorubicin-Induced Cardiomyopathy via Its Anti-Oxidative and Anti-Inflammatory Action

Although the number of patients with heart failure is increasing, a sufficient treatment agent has not been established. Oxidative stress and inflammation play important roles in the development of myocardial remodeling. When thioredoxin (Trx), an endogenous anti-oxidative and inflammatory modulator...

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Detalles Bibliográficos
Autores principales: Murata, Ryota, Watanabe, Hiroshi, Nosaki, Hiroto, Nishida, Kento, Maeda, Hitoshi, Nishida, Motohiro, Maruyama, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953310/
https://www.ncbi.nlm.nih.gov/pubmed/35335938
http://dx.doi.org/10.3390/pharmaceutics14030562