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An Evaluation of CXCR4 Targeting with PAMAM Dendrimer Conjugates for Oncologic Applications

The chemokine receptor 4 (CXCR4) is a promising diagnostic and therapeutic target for the management of various cancers. CXCR4 has been utilized in immunotherapy, targeted drug delivery, and endoradiotherapy. Poly(amidoamine) [PAMAM] dendrimers are well-defined polymers with unique properties that h...

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Detalles Bibliográficos
Autores principales: Lesniak, Wojciech G., Azad, Babak Behnam, Chatterjee, Samit, Lisok, Ala, Pomper, Martin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953329/
https://www.ncbi.nlm.nih.gov/pubmed/35336029
http://dx.doi.org/10.3390/pharmaceutics14030655