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Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway

Weight gain is a hallmark of decreased estradiol (E2) levels because of menopause or following surgical ovariectomy (OVX) at younger ages. Of note, this weight gain tends to be around the abdomen, which is frequently associated with impaired metabolic homeostasis and greater cardiovascular risk in b...

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Detalles Bibliográficos
Autores principales: Romero-Picó, Amparo, Novelle, Marta G., Al-Massadi, Omar, Beiroa, Daniel, Tojo, Marta, Heras, Violeta, Ruiz-Pino, Francisco, Senra, Ana, López, Miguel, Blouet, Clemence, Tena-Sempere, Manuel, Nogueiras, Rubén, Diéguez, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953356/
https://www.ncbi.nlm.nih.gov/pubmed/35328539
http://dx.doi.org/10.3390/ijms23063118