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Sodium-Iodate Injection Can Replicate Retinal Degenerative Disease Stages in Pigmented Mice and Rats: Non-Invasive Follow-Up Using OCT and ERG

Purpose: The lack of suitable animal models for (dry) age-related macular degeneration (AMD) has hampered therapeutic research into the disease, so far. In this study, pigmented rats and mice were systematically injected with various doses of sodium iodate (SI). After injection, the retinal structur...

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Detalles Bibliográficos
Autores principales: Koster, Céline, van den Hurk, Koen T., ten Brink, Jacoline B., Lewallen, Colby F., Stanzel, Boris V., Bharti, Kapil, Bergen, Arthur A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953416/
https://www.ncbi.nlm.nih.gov/pubmed/35328338
http://dx.doi.org/10.3390/ijms23062918