Arginase II protein regulates Parkin-dependent p32 degradation that contributes to Ca(2+)-dependent eNOS activation in endothelial cells

AIMS: Arginase II (ArgII) plays a key role in the regulation of Ca(2+) between the cytosol and mitochondria in a p32-dependent manner. p32 contributes to endothelial nitric oxide synthase (eNOS) activation through the Ca(2+)/CaMKII/AMPK/p38MAPK/Akt signalling cascade. Therefore, we investigated a no...

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Detalles Bibliográficos
Autores principales: Koo, Bon-Hyeock, Won, Moo-Ho, Kim, Young-Myeong, Ryoo, Sungwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953445/
https://www.ncbi.nlm.nih.gov/pubmed/33964139
http://dx.doi.org/10.1093/cvr/cvab163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953445/
https://www.ncbi.nlm.nih.gov/pubmed/33964139
http://dx.doi.org/10.1093/cvr/cvab163

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