Cargando…

Arginase II protein regulates Parkin-dependent p32 degradation that contributes to Ca(2+)-dependent eNOS activation in endothelial cells

AIMS: Arginase II (ArgII) plays a key role in the regulation of Ca(2+) between the cytosol and mitochondria in a p32-dependent manner. p32 contributes to endothelial nitric oxide synthase (eNOS) activation through the Ca(2+)/CaMKII/AMPK/p38MAPK/Akt signalling cascade. Therefore, we investigated a no...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koo, Bon-Hyeock, Won, Moo-Ho, Kim, Young-Myeong, Ryoo, Sungwoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953445/ https://www.ncbi.nlm.nih.gov/pubmed/33964139 http://dx.doi.org/10.1093/cvr/cvab163

Ejemplares similares

Arginase inhibition by rhaponticin increases L-arginine concentration that contributes to Ca(2+)-dependent eNOS activation
por: Koo, Bon-Hyeock, et al.
Publicado: (2021)

Arginase II Contributes to the Ca(2+)/CaMKII/eNOS Axis by Regulating Ca(2+) Concentration Between the Cytosol and Mitochondria in a p32‐Dependent Manner
por: Koo, Bon‐Hyeock, et al.
Publicado: (2018)

p32-Dependent p38 MAPK Activation by Arginase II Downregulation Contributes to Endothelial Nitric Oxide Synthase Activation in HUVECs
por: Koo, Bon-Hyeock, et al.
Publicado: (2020)

Arginase II activity regulates cytosolic Ca(2+) level in a p32-dependent manner that contributes to Ca(2+)-dependent vasoconstriction in native low-density lipoprotein-stimulated vascular smooth muscle cells
por: Koo, Bon-hyeock, et al.
Publicado: (2019)

Overexpressed p32 localized in the endoplasmic reticulum and mitochondria negatively regulates calcium-dependent endothelial nitric oxide synthase activity
por: Choi, Kwanhoon, et al.
Publicado: (2020)

Arginase-I enhances vascular endothelial inflammation and senescence through eNOS-uncoupling
por: Zhu, Cuicui, et al.
Publicado: (2017)

Arginase II inhibition prevents interleukin-8 production through regulation of p38 MAPK phosphorylation activated by loss of mitochondrial membrane potential in nLDL-stimulated hAoSMCs
por: Koo, Bon-Hyeock, et al.
Publicado: (2018)

Arginase Inhibition Suppresses Native Low-Density Lipoprotein-Stimulated Vascular Smooth Muscle Cell Proliferation by NADPH Oxidase Inactivation
por: Koo, Bon-Hyeock, et al.
Publicado: (2018)

Endothelial arginase II and atherosclerosis
por: Ryoo, Sungwoo, et al.
Publicado: (2011)

PKC-Dependent Phosphorylation of eNOS at T495 Regulates eNOS Coupling and Endothelial Barrier Function in Response to G(+) -Toxins
por: Chen, Feng, et al.
Publicado: (2014)

Arginase Inhibition Restores Peroxynitrite-Induced Endothelial Dysfunction via L-Arginine-Dependent Endothelial Nitric Oxide Synthase Phosphorylation
por: Nguyen, Minh Cong, et al.
Publicado: (2016)

mTOR contributes to endothelium-dependent vasorelaxation by promoting eNOS expression and preventing eNOS uncoupling
por: Wang, Yiying, et al.
Publicado: (2022)

Intravenous administration of piceatannol, an arginase inhibitor, improves endothelial dysfunction in aged mice
por: Nguyen, Minh Cong, et al.
Publicado: (2017)

Rosuvastatin Enhances Angiogenesis via eNOS-Dependent Mobilization of Endothelial Progenitor Cells
por: Zhou, Junlan, et al.
Publicado: (2013)

Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity
por: Murthy, Shubha, et al.
Publicado: (2017)

eNOS-Dependent Antisenscence Effect of a Calcium Channel Blocker in Human Endothelial Cells
por: Hayashi, Toshio, et al.
Publicado: (2014)

A Pivotal Role for Tryptophan 447 in Enzymatic Coupling of Human Endothelial Nitric Oxide Synthase (eNOS): EFFECTS ON TETRAHYDROBIOPTERIN-DEPENDENT CATALYSIS AND eNOS DIMERIZATION
por: Benson, Matthew A., et al.
Publicado: (2013)

Increased arginase II activity contributes to endothelial dysfunction through endothelial nitric oxide synthase uncoupling in aged mice
por: Shin, Woosung, et al.
Publicado: (2012)

Obligatory Role for Endothelial Heparan Sulphate Proteoglycans and Caveolae Internalization in Catestatin-Dependent eNOS Activation
por: Fornero, Sara, et al.
Publicado: (2014)

p38 mitogen-activated protein kinase is involved in arginase-II-mediated eNOS-Uncoupling in Obesity
por: Yu, Yi, et al.
Publicado: (2014)

Neurogranin regulates eNOS function and endothelial activation
por: Cheriyan, Vino T., et al.
Publicado: (2020)

Multiple inducers of endothelial NOS (eNOS) dysfunction in sickle cell disease
por: Hebbel, Robert P., et al.
Publicado: (2021)

Vasoinhibins Prevent Bradykinin-Stimulated Endothelial Cell Proliferation by Inactivating eNOS via Reduction of both Intracellular Ca(2+) Levels and eNOS Phosphorylation at Ser(1179)
por: Thebault, Stéphanie, et al.
Publicado: (2011)

Nitric oxide–dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition
por: Chen, Zhenlong, et al.
Publicado: (2012)

Endothelial NO Production Is Mandatory for Epigallocatechin-3-Gallate–induced Vasodilation: Results From eNOS Knockout (eNOS(−/−)) Mice
por: Lorenz, Mario, et al.
Publicado: (2015)

Glutathionylation Mediates Angiotensin II–Induced eNOS Uncoupling, Amplifying NADPH Oxidase‐Dependent Endothelial Dysfunction
por: Galougahi, Keyvan Karimi, et al.
Publicado: (2014)

Nafamostat mesilate promotes endothelium-dependent vasorelaxation via the Akt-eNOS dependent pathway
por: Choi, Sujeong, et al.
Publicado: (2016)

LAV-BPIFB4 isoform modulates eNOS signalling through Ca(2+)/PKC-alpha-dependent mechanism
por: Spinelli, Chiara Carmela, et al.
Publicado: (2017)

Estrogen-Dependent Dynamic Profile of eNOS-DNA Associations in Prostate Cancer
por: Nanni, Simona, et al.
Publicado: (2013)

Rutaecarpine Increases Nitric Oxide Synthesis via eNOS Phosphorylation by TRPV1-Dependent CaMKII and CaMKKβ/AMPK Signaling Pathway in Human Endothelial Cells
por: Lee, Gi Ho, et al.
Publicado: (2021)

Korean red ginseng inhibits arginase and contributes to endotheliumdependent vasorelaxation through endothelial nitric oxide synthase coupling
por: Shin, Woosung, et al.
Publicado: (2013)

Korean Red Ginseng Water Extract Restores Impaired Endothelial Function by Inhibiting Arginase Activity in Aged Mice
por: Choi, Kwanhoon, et al.
Publicado: (2014)

Molecular mechanisms underlying pharmacological stimulation of eNOS expression and eNOS activity
por: Li, Huige, et al.
Publicado: (2009)

Endothelial cell-specific loss of eNOS differentially affects endothelial function
por: Bu, Shuhan, et al.
Publicado: (2022)

eNOS expression in umbilical cord arterial endothelial cells depends on placental perfusion and is triggered by adaptive chromatin signatures
por: Postberg, Jan, et al.
Publicado: (2013)

β-catenin promotes endothelial survival by regulating eNOS activity and flow-dependent anti-apoptotic gene expression
por: Tajadura, Virginia, et al.
Publicado: (2020)

Carbon monoxide prevents TNF-α-induced eNOS downregulation by inhibiting NF-κB-responsive miR-155-5p biogenesis
por: Choi, Seunghwan, et al.
Publicado: (2017)

Reciprocal regulation of eNOS and caveolin-1 functions in endothelial cells
por: Chen, Zhenlong, et al.
Publicado: (2018)

Sex-specific eNOS activity and function in human endothelial cells
por: Cattaneo, Maria Grazia, et al.
Publicado: (2017)

Resting Tension Affects eNOS Activity in a Calcium-Dependent Way in Airways
por: Kitsiopoulou, Eudoxia, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_jlcsbvfvtrbkku45nsdcp0lgra