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Central role of c-Src in NOX5- mediated redox signalling in vascular smooth muscle cells in human hypertension

AIMS: NOX-derived reactive oxygen species (ROS) are mediators of signalling pathways implicated in vascular smooth muscle cell (VSMC) dysfunction in hypertension. Among the numerous redox-sensitive kinases important in VSMC regulation is c-Src. However, mechanisms linking NOX/ROS to c-Src are unclea...

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Detalles Bibliográficos
Autores principales: Camargo, Livia L, Montezano, Augusto C, Hussain, Misbah, Wang, Yu, Zou, Zhiguo, Rios, Francisco J, Neves, Karla B, Alves-Lopes, Rheure, Awan, Fazli R, Guzik, Tomasz J, Jensen, Thomas, Hartley, Richard C, Touyz, Rhian M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953456/
https://www.ncbi.nlm.nih.gov/pubmed/34320175
http://dx.doi.org/10.1093/cvr/cvab171