Development and Performance Verification of the PBPK Model for Antazoline and Its Metabolite and Its Utilization for Pharmacological Hypotheses Formulating

Antazoline is an antihistaminic drug that is effective in the termination of paroxysmal atrial fibrillation. Despite its long presence in the market, antazoline’s ADME parameters and pharmacokinetic effects in humans are poorly characterized. The objective of this study was to fill this gap by gener...

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Detalles Bibliográficos
Autores principales: Wiśniowska, Barbara, Giebułtowicz, Joanna, Piotrowski, Roman, Kułakowski, Piotr, Polak, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953460/
https://www.ncbi.nlm.nih.gov/pubmed/35337175
http://dx.doi.org/10.3390/ph15030379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953460/
https://www.ncbi.nlm.nih.gov/pubmed/35337175
http://dx.doi.org/10.3390/ph15030379

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