Development of the Validated Stability-Indicating Method for the Determination of Vortioxetine in Bulk and Pharmaceutical Formulation by HPLC-DAD, Stress Degradation Kinetics Studies and Detection of Degradation Products by LC-ESI-QTOF-MS

Vortioxetine (VOR) is a new antidepressant drug used to treat major depressive disorder. In this work, a novel, simple, rapid, accurate, precise, selective, stability-indicating, and fully validated high-performance liquid chromatography method with diode array detection (HPLC-DAD) was developed to...

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Detalles Bibliográficos
Autores principales: Wróblewski, Karol, Szultka-Młyńska, Małgorzata, Janiszewska, Daria, Petruczynik, Anna, Buszewski, Bogusław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953571/
https://www.ncbi.nlm.nih.gov/pubmed/35335245
http://dx.doi.org/10.3390/molecules27061883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953571/
https://www.ncbi.nlm.nih.gov/pubmed/35335245
http://dx.doi.org/10.3390/molecules27061883

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