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UME6 Is Involved in the Suppression of Basal Transcription of ABC Transporters and Drug Resistance in the ρ(+) Cells of Saccharomyces cerevisiae

In Saccharomyces cerevisiae, the Rpd3L complex contains a histone deacetylase, Rpd3, and the DNA binding proteins, Ume6 and Ash1, and acts as a transcriptional repressor or activator. We previously showed that RPD3 and UME6 are required for the activation of PDR5, which encodes a major efflux pump,...

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Detalles Bibliográficos
Autor principal: Yamada, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953597/
https://www.ncbi.nlm.nih.gov/pubmed/35336175
http://dx.doi.org/10.3390/microorganisms10030601