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UME6 Is Involved in the Suppression of Basal Transcription of ABC Transporters and Drug Resistance in the ρ(+) Cells of Saccharomyces cerevisiae
In Saccharomyces cerevisiae, the Rpd3L complex contains a histone deacetylase, Rpd3, and the DNA binding proteins, Ume6 and Ash1, and acts as a transcriptional repressor or activator. We previously showed that RPD3 and UME6 are required for the activation of PDR5, which encodes a major efflux pump,...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953597/ https://www.ncbi.nlm.nih.gov/pubmed/35336175 http://dx.doi.org/10.3390/microorganisms10030601 |