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Ceramide-1-phosphate transfer protein promotes sphingolipid reorientation needed for binding during membrane interaction

Lipid transfer proteins acquire and release their lipid cargoes by interacting transiently with source and destination biomembranes. In the GlycoLipid Transfer Protein (GLTP) superfamily, the two-layer all-α-helical GLTP-fold defines proteins that specifically target sphingolipids (SLs) containing e...

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Detalles Bibliográficos
Autores principales: Gao, Yong-Guang, McDonald, Jeffrey, Malinina, Lucy, Patel, Dinshaw J., Brown, Rhoderick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953657/
https://www.ncbi.nlm.nih.gov/pubmed/34808193
http://dx.doi.org/10.1016/j.jlr.2021.100151