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LRP1 loss in airway epithelium exacerbates smoke-induced oxidative damage and airway remodeling

The LDL receptor-related protein 1 (LRP1) partakes in metabolic and signaling events regulated in a tissue-specific manner. The function of LRP1 in airways has not been studied. We aimed to study the function of LRP1 in smoke-induced disease. We found that bronchial epithelium of patients with chron...

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Detalles Bibliográficos
Autores principales: Garcia-Arcos, Itsaso, Park, Sangmi S., Mai, Michelle, Alvarez-Buve, Roger, Chow, Lillian, Cai, Huchong, Baumlin-Schmid, Nathalie, Agudelo, Christina W., Martinez, Jennifer, Kim, Michael D., Dabo, Abdoulaye J., Salathe, Matthias, Goldberg, Ira J., Foronjy, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953659/
https://www.ncbi.nlm.nih.gov/pubmed/35202607
http://dx.doi.org/10.1016/j.jlr.2022.100185