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Comparative Analysis of microRNA Binding Site Distribution and microRNA-Mediated Gene Expression Repression of Oncogenes and Tumor Suppressor Genes

MicroRNAs (miRNAs) are a family of short, noncoding RNAs that can regulate gene expression levels of over half of the human genome. Previous studies on the role of miRNAs in cancer showed overall widespread downregulation of miRNAs as a hallmark of human cancer, though individual miRNAs can be both...

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Detalles Bibliográficos
Autores principales: Tian, Shuangmei, Wang, Jing, Zhang, Fangyuan, Wang, Degeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953695/
https://www.ncbi.nlm.nih.gov/pubmed/35328035
http://dx.doi.org/10.3390/genes13030481