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Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis

High levels of circulating triglycerides (TGs), or hypertriglyceridemia, are key components of metabolic diseases, such as type 2 diabetes, metabolic syndrome, and CVD. As TGs are carried by lipoproteins in plasma, hypertriglyceridemia can result from overproduction or lack of clearance of TG-rich l...

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Detalles Bibliográficos
Autores principales: Whitacre, Brynne E., Howles, Philip, Street, Scott, Morris, Jamie, Swertfeger, Debi, Davidson, W. Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953696/
https://www.ncbi.nlm.nih.gov/pubmed/34863862
http://dx.doi.org/10.1016/j.jlr.2021.100157