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Detection of Target Genes for Drug Repurposing to Treat Skeletal Muscle Atrophy in Mice Flown in Spaceflight

Skeletal muscle atrophy is a common condition in aging, diabetes, and in long duration spaceflights due to microgravity. This article investigates multi-modal gene disease and disease drug networks via link prediction algorithms to select drugs for repurposing to treat skeletal muscle atrophy. Key t...

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Detalles Bibliográficos
Autores principales: Manian, Vidya, Orozco-Sandoval, Jairo, Diaz-Martinez, Victor, Janwa, Heeralal, Agrinsoni, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953707/
https://www.ncbi.nlm.nih.gov/pubmed/35328027
http://dx.doi.org/10.3390/genes13030473