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Anabolic Function Downstream of TOR Controls Trade-offs Between Longevity and Reproduction at the Level of Specific Tissues in C. elegans

As the most energetically expensive cellular process, translation must be finely tuned to environmental conditions. Dietary restriction attenuates signaling through the nutrient sensing mTOR pathway, which reduces translation and redirects resources to preserve the soma. These responses are associat...

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Detalles Bibliográficos
Autores principales: Howard, Amber C., Mir, Dilawar, Snow, Santina, Horrocks, Jordan, Sayed, Hussein, Ma, Zhengxin, Rogers, Aric N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953723/
https://www.ncbi.nlm.nih.gov/pubmed/35340273
http://dx.doi.org/10.3389/fragi.2021.725068