A Deeper Insight in Metal Binding to the hCtr1 N-terminus Fragment: Affinity, Speciation and Binding Mode of Binuclear Cu(2+) and Mononuclear Ag(+) Complex Species

Ctr1 regulates copper uptake and its intracellular distribution. The first 14 amino acid sequence of the Ctr1 ectodomain Ctr1((1-14)) encompasses the characteristic Amino Terminal Cu(2+) and Ni(2+) binding motif (ATCUN) as well as the bis-His binding motif (His5 and His6). We report a combined therm...

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Detalles Bibliográficos
Autores principales: Magrì, Antonio, Tabbì, Giovanni, Naletova, Irina, Attanasio, Francesco, Arena, Giuseppe, Rizzarelli, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953729/
https://www.ncbi.nlm.nih.gov/pubmed/35328348
http://dx.doi.org/10.3390/ijms23062929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953729/
https://www.ncbi.nlm.nih.gov/pubmed/35328348
http://dx.doi.org/10.3390/ijms23062929

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