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A Deeper Insight in Metal Binding to the hCtr1 N-terminus Fragment: Affinity, Speciation and Binding Mode of Binuclear Cu(2+) and Mononuclear Ag(+) Complex Species
Ctr1 regulates copper uptake and its intracellular distribution. The first 14 amino acid sequence of the Ctr1 ectodomain Ctr1((1-14)) encompasses the characteristic Amino Terminal Cu(2+) and Ni(2+) binding motif (ATCUN) as well as the bis-His binding motif (His5 and His6). We report a combined therm...
Autores principales: | Magrì, Antonio, Tabbì, Giovanni, Naletova, Irina, Attanasio, Francesco, Arena, Giuseppe, Rizzarelli, Enrico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953729/ https://www.ncbi.nlm.nih.gov/pubmed/35328348 http://dx.doi.org/10.3390/ijms23062929 |
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