Detection of Label-Free Drugs within Brain Tissue Using Orbitrap Secondary Ion Mass Spectrometry as a Complement to Neuro-Oncological Drug Delivery

Historically, pre-clinical neuro-oncological drug delivery studies have exhaustively relied upon overall animal survival as an exclusive measure of efficacy. However, with no adopted methodology to both image and quantitate brain parenchyma penetration of label-free drugs, an absence of efficacy typ...

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Detalles Bibliográficos
Autores principales: McCrorie, Phoebe, Rowlinson, Jonathan, Scurr, David J., Marlow, Maria, Rahman, Ruman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953756/
https://www.ncbi.nlm.nih.gov/pubmed/35335947
http://dx.doi.org/10.3390/pharmaceutics14030571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953756/
https://www.ncbi.nlm.nih.gov/pubmed/35335947
http://dx.doi.org/10.3390/pharmaceutics14030571

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