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Enhancement of the Solubility and Bioavailability of Pitavastatin through a Self-Nanoemulsifying Drug Delivery System (SNEDDS)

The purpose of the study was to develop an SNEDDS to improve the solubility and bioavailability of pitavastatin. The solubility of pitavastatin in different oils, surfactants, and co-surfactants was determined and a pseudo-ternary phase diagram was constructed. The SNEDDS was characterized by zeta-s...

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Detalles Bibliográficos
Autores principales: Ashfaq, Mehran, Shah, Shahid, Rasul, Akhtar, Hanif, Muhammad, Khan, Hafeez Ullah, Khames, Ahmed, Abdelgawad, Mohamed A., Ghoneim, Mohammed M., Ali, Muhammad Yasir, Abourehab, Mohammad A. S., Maheen, Safirah, Iqbal, Omeira, Abbas, Ghulam, El Sisi, Amani M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953816/
https://www.ncbi.nlm.nih.gov/pubmed/35335860
http://dx.doi.org/10.3390/pharmaceutics14030482