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Enhancement of the Solubility and Bioavailability of Pitavastatin through a Self-Nanoemulsifying Drug Delivery System (SNEDDS)
The purpose of the study was to develop an SNEDDS to improve the solubility and bioavailability of pitavastatin. The solubility of pitavastatin in different oils, surfactants, and co-surfactants was determined and a pseudo-ternary phase diagram was constructed. The SNEDDS was characterized by zeta-s...
Autores principales: | Ashfaq, Mehran, Shah, Shahid, Rasul, Akhtar, Hanif, Muhammad, Khan, Hafeez Ullah, Khames, Ahmed, Abdelgawad, Mohamed A., Ghoneim, Mohammed M., Ali, Muhammad Yasir, Abourehab, Mohammad A. S., Maheen, Safirah, Iqbal, Omeira, Abbas, Ghulam, El Sisi, Amani M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953816/ https://www.ncbi.nlm.nih.gov/pubmed/35335860 http://dx.doi.org/10.3390/pharmaceutics14030482 |
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