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Identifying Function Determining Residues in Neuroimmune Semaphorin 4A

Semaphorin 4A (Sema4A) exerts a stabilizing effect on human Treg cells in PBMC and CD4+ T cell cultures by engaging Plexin B1. Sema4A deficient mice display enhanced allergic airway inflammation accompanied by fewer Treg cells, while Sema4D deficient mice displayed reduced inflammation and increased...

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Detalles Bibliográficos
Autores principales: Chapoval, Svetlana P., Lee, Mariah, Lemmer, Aaron, Ajayi, Oluwaseyi, Qi, Xiulan, Neuwald, Andrew F., Keegan, Achsah D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953949/
https://www.ncbi.nlm.nih.gov/pubmed/35328445
http://dx.doi.org/10.3390/ijms23063024