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Exosomal Carboxypeptidase E (CPE) and CPE-shRNA-Loaded Exosomes Regulate Metastatic Phenotype of Tumor Cells

Background: Exosomes promote tumor growth and metastasis through intercellular communication, although the mechanism remains elusive. Carboxypeptidase E (CPE) supports the progression of different cancers, including hepatocellular carcinoma (HCC). Here, we investigated whether CPE is the bioactive c...

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Detalles Bibliográficos
Autores principales: Hareendran, Sangeetha, Albraidy, Bassam, Yang, Xuyu, Liu, Aiyi, Breggia, Anne, Chen, Clark C., Loh, Y. Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953963/
https://www.ncbi.nlm.nih.gov/pubmed/35328535
http://dx.doi.org/10.3390/ijms23063113