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STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS)
Stimulator of interferon genes (STING) contributes to immune responses against tumors and may control viral infection including SARS-CoV-2 infection. However, activation of the STING pathway by airway silica or smoke exposure leads to cell death, self-dsDNA release, and STING/type I IFN dependent ac...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953969/ https://www.ncbi.nlm.nih.gov/pubmed/35338116 http://dx.doi.org/10.1038/s41419-022-04664-5 |