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STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS)

Stimulator of interferon genes (STING) contributes to immune responses against tumors and may control viral infection including SARS-CoV-2 infection. However, activation of the STING pathway by airway silica or smoke exposure leads to cell death, self-dsDNA release, and STING/type I IFN dependent ac...

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Detalles Bibliográficos
Autores principales: Messaoud-Nacer, Yasmine, Culerier, Elodie, Rose, Stéphanie, Maillet, Isabelle, Rouxel, Nathalie, Briault, Sylvain, Ryffel, Bernhard, Quesniaux, Valerie F. J., Togbe, Dieudonnée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953969/
https://www.ncbi.nlm.nih.gov/pubmed/35338116
http://dx.doi.org/10.1038/s41419-022-04664-5