Iridium(I)-Catalyzed Isoindolinone-Directed Branched-Selective Aromatic C–H Alkylation with Simple Alkenes

We report an iridium(I)-catalyzed branched-selective C–H alkylation of N-arylisoindolinones with simple alkenes as the alkylating agents. The amide carbonyl group of the isoindolinone motif acts as the directing group to assist the ortho C–H activation of the N-aryl ring. With this atom-economic and...

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Detalles Bibliográficos
Autores principales: Xiong, Maoqian, Shu, Yuhang, Tang, Jie, Yang, Fan, Xing, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954050/
https://www.ncbi.nlm.nih.gov/pubmed/35335286
http://dx.doi.org/10.3390/molecules27061923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954050/
https://www.ncbi.nlm.nih.gov/pubmed/35335286
http://dx.doi.org/10.3390/molecules27061923

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