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Mechanochemical Effect on Controlled Drug Release of Konjac Glucomannan Matrix Tablets during Dry Grinding

To design a controlled drug release preparation based on a safe natural material, a Konjac glucomannan (KGM) mixture containing 16.0 w/w% calcium hydroxide (Ca(OH)(2)) was ground in a planetary ball mill for 0–120 min. The mechanochemical effect on the physicochemical properties of the KGM ground pr...

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Detalles Bibliográficos
Autores principales: Okazaki, Fuminori, Hattori, Yusuke, Sasaki, Tetsuo, Otsuka, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954073/
https://www.ncbi.nlm.nih.gov/pubmed/35323294
http://dx.doi.org/10.3390/gels8030181