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A Small-Plaque Isolate of the Zika Virus with Envelope Domain III Mutations Affect Viral Entry and Replication in Mammalian but Not Mosquito Cells

An Asian Zika virus (ZIKV) isolated from a Thai patient that was serially passaged in Primary Dog Kidney (PDK) cells for attenuation displayed both big and small plaque-forming viruses by the 7th passage. Two small-plaque isolates were selected and purified for characterization as attenuated ZIKV ca...

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Detalles Bibliográficos
Autores principales: Jaimipuk, Thitigun, Sachdev, Saranya, Yoksan, Sutee, Thepparit, Chutima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954177/
https://www.ncbi.nlm.nih.gov/pubmed/35336887
http://dx.doi.org/10.3390/v14030480