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Recent Development of Prodrugs of Gemcitabine

Gemcitabine is a nucleoside analog that has been used widely as an anticancer drug for the treatment of a variety of conditions, including ovarian, bladder, non-small-cell lung, pancreatic, and breast cancer. However, enzymatic deamination, fast systemic clearance, and the emergence of chemoresistan...

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Detalles Bibliográficos
Autores principales: Pandit, Bhoomika, Royzen, Maksim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954202/
https://www.ncbi.nlm.nih.gov/pubmed/35328020
http://dx.doi.org/10.3390/genes13030466