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Synthesis and Evaluation of a (18)F-Labeled Ligand for PET Imaging of Colony-Stimulating Factor 1 Receptor

Neuroinflammation involves activation of glial cells in the brain, and activated microglia play a particularly important role in neurodegenerative diseases such as Alzheimer’s disease (AD). In this study, we developed 5-cyano-N-(4-(4-(2-[(18)F]fluoroethyl)piperazin-1-yl)-2-(piperidin-1-yl)phenyl)fur...

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Detalles Bibliográficos
Autores principales: Lee, Hyeokjin, Park, Ji-Hun, Kim, Hyunjung, Woo, Sang-keun, Choi, Joon Young, Lee, Kyung-Han, Choe, Yearn Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954204/
https://www.ncbi.nlm.nih.gov/pubmed/35337075
http://dx.doi.org/10.3390/ph15030276