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Prospective multicentre head-to-head validation of host blood transcriptomic biomarkers for pulmonary tuberculosis by real-time PCR

BACKGROUND: Sensitive point-of-care screening tests are urgently needed to identify individuals at highest risk of tuberculosis. We prospectively tested performance of host-blood transcriptomic tuberculosis signatures. METHODS: Adults without suspicion of tuberculosis were recruited from five endemi...

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Detalles Bibliográficos
Autores principales: Mendelsohn, Simon C., Mbandi, Stanley Kimbung, Fiore-Gartland, Andrew, Penn-Nicholson, Adam, Musvosvi, Munyaradzi, Mulenga, Humphrey, Fisher, Michelle, Hadley, Katie, Erasmus, Mzwandile, Nombida, Onke, Tameris, Michèle, Walzl, Gerhard, Naidoo, Kogieleum, Churchyard, Gavin, Hatherill, Mark, Scriba, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954216/
https://www.ncbi.nlm.nih.gov/pubmed/35342900
http://dx.doi.org/10.1038/s43856-022-00086-8