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Prospective multicentre head-to-head validation of host blood transcriptomic biomarkers for pulmonary tuberculosis by real-time PCR
BACKGROUND: Sensitive point-of-care screening tests are urgently needed to identify individuals at highest risk of tuberculosis. We prospectively tested performance of host-blood transcriptomic tuberculosis signatures. METHODS: Adults without suspicion of tuberculosis were recruited from five endemi...
Autores principales: | Mendelsohn, Simon C., Mbandi, Stanley Kimbung, Fiore-Gartland, Andrew, Penn-Nicholson, Adam, Musvosvi, Munyaradzi, Mulenga, Humphrey, Fisher, Michelle, Hadley, Katie, Erasmus, Mzwandile, Nombida, Onke, Tameris, Michèle, Walzl, Gerhard, Naidoo, Kogieleum, Churchyard, Gavin, Hatherill, Mark, Scriba, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954216/ https://www.ncbi.nlm.nih.gov/pubmed/35342900 http://dx.doi.org/10.1038/s43856-022-00086-8 |
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